What's new

Smart infusion pumps

Guide updated to include smart infusion pumps and link to practice guideline, resources and medication libraries.

Specialised routes of administration 

Guide updated to include  epidural, intra-articular, intraosseus, intrthecal, intracameral, intravitreal injection.

Hazardous medicines

Guide updated to include hazardous medicines and link to local guidelines.

Compatible fluids

Guide updated to include: "If  a medicine is compatible in single component IV fluids e.g. G5W and NS,  it does not infer that it is compatible in a combination IV fluid of the individual component IV fluids e.g. G5W/NS."

PVC-free lines

Examples of medicines that adsorb to PVC and medicines that leach toxic plasticisers have been added under the "Guide" tab.

Plasma-Lyte 148

Product Information information link aded to Plasma-Lyte Guide tab under the Guide tab.

Flushing guide update

Appendices update

Intravenous fluid bag compositions have been added to the appendices

Standard parenteral nutrition solutions composition have been added to the "Appendices" with a link to the  SCHN Parenteral Nutrition Practice Guideline  which also appears on the "Guide" tab under IV compatibility, Medicine compatibility with parenteral nutrition.

New and updated monographs

The online version of The Paediatric Injectable Medicines Handbook is periodically updated. New medicine monographs are added and existing monographs are reviewed. The date of addition of new monographs or a full review of individual medicines appear at the bottom of the monograph.

January–February 2024
New Monographs Updated Monographs
  • Peramivir
  • Sebelipase alfa
  • Semaglutide
  • Tadalafil
  • Acetylcysteine: revised compatibility, links.
  • Acetazolamide: included S19A Mylan brands for injection and link to Product Information.
  • Adrenaline (epinephrine): added excipents; revised brands, preparation, stability, administration, cautions.
  • Alfentanil: revised brands, IV injection concentration, dilution.
  • Bupivacaine: revised products, stability.
  • Cefotaxime: revised maximum concentration for infusion.
  • Ceftriaxone: revised brands, dilution, revised IV injection.
  • Dopamine: revised preparation, stability, administration (flushing), compatibility (added Plasma-lyte 148), adverse effects, monitoring.
  • Esomeprazole: updated IV administration.
  • Esmolol: revised IV dilution, administration.
  • Fentanyl: added dilution examples, excipients, revised preparation, stability,  administration, compatibility (added Plasma-lyte 148), caution. 
  • Glyceryl trinitrate
  • Heparin: revised products; cautions.
  • Hyoscine Hydrobromide: revised rate.
  • Hyoscine Butylbromide: revised rate.
  • Levocarnitine: revised brans, compatibility, adverse effects.
  • Magnesium Chloride: added contraindications, adverse effects, equivalent mg and mmol conversion, link to Anmf, revised monitoring, products, storage, preparation.
  • Magnesium Sulfate: added contraindications, adverse effects, equivalent mg and mmol conversion, link to Anmf, revised monitoring, products, storage, preparation.
  • Methadone: included comment on off-label IV route.
  • Oxycodone: added dilution example, excipents; revised brands, administration.
  • Paracetamol
  • Ropivacaine: revised products, stability, monitoring,.
  • Sodium benzoate: added dilution example.
  • Tacrolimus: revised cautions.
  • Vancomycin: added dilution examples, intravitreal injection, link to ANMF, excipients, plasma-lyte; revised brands; preparation,administration, compatible fluids
  • Vitamin B12: revised brands, preparation.
July–December 2023  
New Monographs Updated Monographs
  • Artesunate
  • Benralizumab
  • Isavuconazole
  • Nirsevimab
  • Sodium phenylbutyrate
  • Vosoritide
  • Antithymocyte Globulin Equine: added dilution example, revised brands, preparation, excipients.  
  • Antithymocyte Globulin Rabbit: added dilution example, revised brands, preparation, excipients. 
  • Benzathine benzyl penicillin: added S19A product, part-doses, excipients; revised storage, preparation, administration, cautions.
  • Calcitriol: revised adverse effects and monitoring.
  • Dexamethasone: added dilution examples, adverse effects, excipients, revised preparation, administration.
  • Furosemide: added adverse effects, dilution example; revised administration, compatible fluids. 
  • Levosimendan: added dilution examples, revised products, administration, caution, excipients. 
  • Naloxone: added dilution examples, revised preparation, rates.
  • Omeprazole: revised continuous administration.
  • Parecoxib: added contraindications, adverse effects; revised duration to withholding NSAIDs for 12 hours after parecoxib dose, revised brands.
  • Prochlorperazine: added adverse effects, excipients, revised monitoring, administration.
  • Ribavirin: deleted monograph. IV discontinued.
  • Salbutamol: added dilution examples.
  • Sodium bicarbonate: added link to ANMF, revised brands, stability, administration, comments.
  • Vancomycin: added dilution examples, intravitreal administration, excipients; revised brands, preparation, stability, compatible fluids, adverse effects, monitoring.
  • Vitamin B6: added subcut route; revised adverse effects, compatibility.
  • Vitamin C: revised strength, administration, cautions.
  • Voriconazole: revised dilution example.

January to June 2023

  

New Monographs

Updated Monographs
  • Baclofen
  • Albumin: added dilution examples, excipients, revised preparation, stability, administration, adverse effects, monitoring. 
  • Amoxicillin: added adverse effects, monitoring; revised preparation, stability, brands.
  • Amoxicillin with clavulanic acid: revised dilution examples, administration, adverse effects, monitoring, excipients.
  • Ampicillin: added dilution examples, continuous infusion, revised administration rates.
  • Azithromycin: revised compatibility, adverse effects, monitoring.
  • Benzatropine: added stability, adverse effects, monitoring; revised brand, preparation, stability, administration.
  • Benzylpenicillin sodium: revised rates.
  • Brivaracetam: added dilution example, monitoring; revised administration, adverse effects.
  • Calcium chloride: added equivalent mmol concentration and dilution example; updated links.
  • Calcium gluconate: added dilution examples, revised product, rates, updated links.
  • Chlorpromazine: added monitoring, excipients; revised preparation, administration, adverse effects.
  • Clindamycin: added dilution example, link to ANMF, adverse effects, monitoring; revised brands, stability, compatibilities. 
  • Desferrioxamine: added dilution examples, revised administration.
  • Diazepam: added excipients, revised preparation, stability, administration, adverse effects, monitoring.
  • Ferric carboxymaltose: added cautions, adverse effects, revised administration, monitoring.
  • Iron polymaltose: revised stability, administration, adverse effects.
  • Isoprenaline: added dilution examples, link to ANMF monograph, caution, excipients; revised stability, administration, compatible fluids (Plasma-lyte 148), adverse effects, monitoring.
  • Labetalol: added dilution example, rates; revised preparation, compatibility, monitoring.
  • Levetiracetam: revised brands, stability, administration.
  • Lincomycin: added dilution example, adverse effects, monitoring; revised administration, stability, compatibilities. 
  • Metoprolol: added stability, revised administration, adverse effects, and monitoring.
  • Palivizumab: added link to ANMF, revised stability, adverse effects.
  • Rasburicase: revised preparation, stability, administration, monitoring.
  • Sildenafil: added adverse effects, revised dilution examples, stability, administration, monitoring. 
  • Tacrolimus: added dilution example, revised stability.
  • Tocilizumab: added prefilled syringe and pen; subcut administration; revised stability.
  • Urokinase: revised brands, reconstitution (diluent is brand specific).
  • Valproate sodium: added dilution examples, monitoring; revised preparation, stability, administration (status epileticus), monitoring.
  • Vitamin B12: revised brands, preparation.

January–December 2022

New Monographs

Updated Monographs
  • Abatacept
  • Levothroxine
  • Palonosetron
  • Procainamide
  • Triptoreline
  • Acetazolamide: added excipients; revised pH, stability, administration, adverse effects, monitoring.
  • Amiodarone: revised use of filter recommendation.
  • Azathioprine: added cautions, excipients, revised preparation, administration, adverse effects, monitoring.
  • Basiliximab: added dilution example, cautions, excipients, premedication; revised adverse effects, monitoring.
  • Botulinum toxin type A (Botox): added monitoring
  • Clonidine: added dilution example, revised compatible fluids (added plasma-lyte 148).
  • Cyclizine: revised administration.
  • Droperidol: added excipients; revised brands, preparation, administration, cautions, adverse effects, monitoring.
  • Esomeprazole: added dilution example; revised stability; compatibility (added Plasma-lyte 148).
  • Filgrastim: added adverse effects, excipients, revised products, preparation, administration,  comments
  • Flucloxacillin: revised stability information for continuous infusion solutions.
  • Folinic acid (Leucovorin calcium): added monitoring; revised therapeutic class, pH, stability.
  • Gentamicin: added dilution examples,  link to ANMF,  cautions, excipients; revised products, stability, administration, compatible fluids (added plasma-lyte 148).
  • Glucagon: revised preparation, stability, administration; compatibilities, monitoring.
  • Heparin: revised products, preparation, stability, administration; compatibilities, adverse effects, monitoring.
  • Hydromorphone: added contraindications, adverse effects; revised brands, preparation, administration, cautions, compatible fluids (added plasma-lyte 148).
  • Levocarnitine: added excipients; revised preparation, stability.
  • Lidocaine: added dilution examples; revised brands, preparation, stability, compatibility (added plasma-lyte 148).
  • Octreotide: added link to AMH-CDC and ANMF, interactions, adverse effects; revised indications, chylothorax dose, restrictions, monitoring, links to policies.
  • Omeprazole: added dilution example; link to ANMF.
  • Ondansetron: added monitoring, excipients; revised brands, stability, compatible fluids.
  • Pamidronate: added excipients, cautions; revised brands, preparation.
  • Pantoprazole: added dilution examples; revised brands, pH, stability, administration, compatible fluids.
  • Pentamidine isethionate: added dilution example; revised preparation, stability, administration, cautions, monitoring, adverse effects.
  • Potassium chloride: revised brands, preparation, stability, compatible fluids (added Plasma-lyte 148), added link to policy.
  • Potassium dihydrogen phosphate: added contraindications, cautions, revised preparation, administration, adverse effects, monitoring.
  • Protamine: revised administration, compatible fluids (added Plasma-lyte 148).
  • Remdesivir: added SBECD injection liquid vial SBECD risk; dilution for <40 kg, link to ANMF, extravasation risk.
  • Ribavirin: added stability, cautions, adverse effects, revised administration.
  • Sodium calcium edetate: updated poisons information centre contact details.
  • Sodium chloride: revised available products, preparation, rates, adverse effects, monitoring.
  • Sodium dihydrogen phosphate: added adverse effects, excipients; revised preparation, stability, administration, monitoring.
  • Sotalol: added dilution example
  • Tetracosactide: added dilution example for low dose adrenal insufficiency test and IV administration guidelines.
  • Thiopental: revised dilution examples
  • Urokinase: added excipients; updated brands, available strengths, preparation, stability, compatible fluids.\
  • Voriconazole: revised brands, administration, added excipients

January–December 2021

New monographs

Updated monographs
  • Alpha lipoic acid
  • Aspirin
  • Dexpanthenol
  • Biotin (Vitamin B7 or H)
  • Bivalirudin
  • Calcitriol
  • Diphenydramine
  • Fluorescein
  • Goserelin
  • Tirofiban
  • Cisatracurium
  • Diphenhydramine
  • Eculizumab
  • Methadone
  • Dupilumab
  • Ranibizumab
  • Triamcinolone acetonide
  • Triamcinolone hexacetonide
  • Insulin Biphasic (mixed), Intermediate-acting, Long-acting
  • Insulin Ultra-short Acting
  • Alfentanil
  • Atracurium
  • Betamethasone
  • Botulinium Toxin Type A (Botox)
  • Ceftolozane with tazobactam
  • Ceftazidime with avibactam
  • Etanercept
  • Flecainide
  • Dantrolene
  • Folic acid
  • Hyaluronidase
  • Remdesivir
  • Tetrasocatride
  • Amiodarone: revised brands, storage, preparation (added dilution examples), stability, administration, compatibility, added adverse effects, monitoring.
  • Amoxicillin with clavulanic acid: revised preparation (added dilution examples); revised stability, administration, added cautions, monitoring.
  • Amoxicillin: revised preparation (IM) and administration; added dilution examples.
  • Amphotericin B-Liposomal: added link to SCHN Empiric Antifungal treatment: Management of paediatric haematology, Oncology and Haematopoietic Stem Cell Transplant Patients Practice Guideline.
  • Aprotinin: revised brands, administration, adverse effects, added monitoring, excipients and link to SAS PI.
  • Argipressin (vasopressin): added link to ANMF.
  • Atracurium: revised cautions, adverse effects, monitoring.
  • Atropine: revised preparation, stability, administration (flushing); compatibilities, adverse effects, monitoring, added excipients.
  • Aztreonam: added dilution examples, revised maximum IV injection concentration and stability.
  • Bevacizumab: added dilution examples, pre-medication, excipients; revised storage, administration, cautions monitoring.
  • C1 esterase: included preparation, stability and administration for Berinert 1,500 international units.
  • Caffeine citrate: revised preparation (added dilution examples), stability, administration; compatibilities, adverse effects, monitoring.
  • Calcium chloride: revised preparation, stability, administration (flushing), compatibility (added Plasma-lyte 148), adverse effects, monitoring, added excipients.
  • Calcium gluconate: revised preparation, stability, administration (flushing), compatibility (added Plasma-lyte 148), adverse effects, monitoring, cautions, added excipients.
  • Cefazolin: revised brands, preparation (added dilution example), stability, administration (IM), compatible fluids (added plasma-lyte 148), adverse effects and monitoring.
  • Cefotaxime: updated products and preparation (500 mg vial no longer available); revised maximum IM concentration.
  • Cefoxitin: updated displacement volumes.
  • Ceftazidime: revised brands, preparation, stability, administration (IM), compatible fluids (added plasma-lyte 148), added excipients.
  • Ceftoraline: revised preparation, stability, administration, added dilution examples, excipients.
  • Ceftriaxone: revised brands, preparation (added dilution examples), stability, administration (IM), compatible fluids, added adverse effects.
  • Ciclosporin: revised stability, administration, compatibility (added Plasma-lyte 148), cautions.
  • Colistin (as colistimethate sodium): revised sodium content, administration, added adverse effects and monitoring.
  • Cyclizine: revised preparation (added dilution example), revised stability, administration. 
  • Daptomycin: added pH, excipients; revised preparation and stability.
  • Defibrotide: added link to local protocols; excipients.
  • Desmopressin: added excipients; revised brands, preparation, administration, adverse effects.
  • Dexamethasone: revised storage, stability, administration, compatible fluids (added plasma-lyte 148), monitoring, added excipients.
  • Diazepam: added link to e-policy.
  • Ertapenem: revised brands, preparation, stability, administration (IM), adverse effects, added monitoring.
  • Ertapenem: revised intermittent infusion.
  • Erythromycin: added dilution examples.
  • Esmolol: added 2.5 g powdered vial, dilution example, excipients; revised preparation, stability, administration, compatible fluids.
  • Famotidine: updated SAS brands and linked Product Information.
  • Ferric carboxymaltose: added dilution examples, adverse effects, excipients; revised administration, monitoring.
  • Flucloxacillin: revised preparation (added dilution examples), stability, administration; compatibilities, adverse effects, monitoring.
  • Fluconazole: revised brands, preparation, stability, compatible fluids (added plasma-lyte 148), added links to ANMF and  SCHN protocol, excipients.
  • Fomepizole: revised preparation (added dilution example), stability, administration, adverse effects, monitoring.
  • Foscarnet: revised preparation, stability, administration; compatibilities, adverse effects, monitoring.
  • Glyceryl trinitrate: revised brands, products, preparation, administration, compatible fluids (added plasma-Lyte 148), adverse effects, added monitoring, excipients.
  • Hydralazine: revised brands, preparation, administration (IM), cautions, compatible fluids (added plasma-Lyte 148), adverse effects, added monitoring, excipients
  • Hyoscine Butylbromide: revised brands, preparation, stability, administration (flushing), compatibility (added Plasma-lyte 148), cautions, added excipients.
  • Hyoscine Hydrobromide: revised preparation, stability, administration (IM), adverse effects.
  • Ibuprofen: added excipients, link to ANMF; revised preparation, stability, administration.
  • Imipenem-cilastin: revised preparation (added dilution examples), stability, administration; added excipients, link to ANMF
  • Infliximab: revised preparation (added dilution examples), stability, administration; monitoring, adverse effects; added excipients, link to SCHN protocols.
  • Insulin neutral: added dilution examples, excipient, link to SCHN protocols, ANMF; revised  storage, stability, administration; cautions, monitoring.
  • Iron polymaltose: added link to SCHN protocol.
  • Iron sucrose: added dilution examples, excipients, revised stability, administration, cautions, monitoring.
  • Levetiracetam: updated brands (pre-mixed bag discontinued), preparation (added dilution examples), administration, compatible fluids, added monitoring.
  • Levomepromazine: added link to Nozinan SAS product information.
  • Lorazepam: updated brands, preparation, administration, added adverse effects, monitoring, excipients
  • Mannitol: revised preparation, stability; administration, monitoring; added adverse effects, excipients. 
  • Mannitol: revised preparation, stability; administration, monitoring; added adverse effects, excipients. 
  • Meropenem: revised preparation , stability; administration (added extended infusion), adverse effects, monitoring; added link to ANMF, dilution examples, excipients
  • Metaraminol: updated brands, products, pH, preparation, administration, compatible fluids, adverse effects, added monitoring, excipients.
  • Methylprednisolone sodium succinate revised products, preparation (added dilution example), stability, administration (maximum concentration), compatible fluids, added monitoring, excipients.
  • Midazolam: revised IM administration; updated link to e-policy.
  • Moxifloxacin: added adverse effects, monitoring, excipients; revised brands, preparation, administration, compatible fluids (added Plasmalyte 148).
  • Moxifloxacin: revised brands, preparation, administration, compatible fluids (added Plasmalyte 148), added adverse effects, monitoring, excipients.
  • Palivizumab: revised preparation, administration, compatibility, cautions; added excipients.
  • Pancuronium: revised comments.
  • Pancuronium: revised brands (SAS), preparation (added dilution example), stability, administration, cautions, adverse effects, monitoring.
  • Phenobarbital: revised preparation, stability and administration, compatibility, adverse effects, monitoring added link to ANMF and SCHN acute seizure management guideline. 
  • Piperacillin with tazobactam: revised brands, preparation, sodium content.
  • Promethazine: added monitoring and excipients; revised preparation, stability, administration, cautions, adverse effects.
  • Propofol: added link to ANMF.
  • Remdesivir: revised stability when prepared under aseptic conditions in Pharmacy.
  • Rocuronium: revised brands, pH, preparation (added dilution examples); cautions, adverse effects, added monitoring, reversal agent and link to ANMF and local policies.
  • Suxamethonium: added Juno ampoules stability at room temperature.
  • Thiopental: added dilution examples, excipients, adverse effects, monitoring; revised brands, stability, compatible fluids (added Plasma-lyte 148), cautions.
  • Thiopental: revised brands, preparation (added dilution example); adminisatration;  adverse effects; monitoring.
  • Ticarcillin with clavulanic acid: added dilution example, excipients, monitoring; revised brands (now SAS); adverse effects.
  • Tobramycin: added link to ANMF; updated time levels are taken for cystic fibrosis patients.
  • Trimethoprim with sulfamethoxazole: revised preparation, stability; administration, compatible fluids (added Plasma-lyte 148), adverse effects, monitoring; added link to ANMF.
  • Vecuronium: revised  brands, preparation (added dilution example), stability, compatible fluids, adverse effects, monitoring; added cautions, excipients; link to e-policy.
  • Vitamin B1 (Thiamine): revised compatible fluids.
  • Vitamin K1 (Phytomenadione): added link to ANMF, Y-site compatible fluid, excipients; revised stability

January–December 2020

New monographs

Full review and updated monographs
  • Benzathine Benzylpenicillin
  • Brivaracetam
  • Canakinumab
  • Colecalciferol (Vitamin D3)
  • Desferrioxamine
  • Dexmedetomidine
  • Digoxin immune fab
  • Enoxaparin
  • Epoprostenol (Veletri): preferred brand
  • Fosphenytoin
  • Glucose
  • Indocyanine green: diagnostic agent
  • Ketorolac
  • Liothyronine
  • Natalizumab
  • Neostigmine
  • Olanzapine
  • Omalizumab
  • Rituximab
  • Sotalol
  • Sugammadex
  • Tigecycline
  • Ustekinumab
  • Vedolizumab
  • Vitamin E
  • Acetylcysteine: deleted 3-stage infusion, revised comments, added excipients
  • Adenosine: updated available products, preparation, stability, comments; added link to ANMF, excipients
  • Alprostadil: updated available products, preparation, stability, administration (added link to ANMF), compatible fluids, monitoring, adverse effects; added excipients
  • Alteplase: revised preparation, stability, administration for occluded catheter, monitoring
  • Amikacin: revised available products, preparation, stability, comments, added excipients
  • Aminophylline: updated preparation, administration (added link to Acute asthma management policy), monitoring, adverse effects
  • Amoxicillin: revised available products, preparation, stability, administration, compatibility, cautions, added excipients
  • Ampicillin: updated preparation, stability, administration (added link to ANMF), monitoring, adverse effects
  • Arginine: updated preparation, stability, administration (included pituitary function test); comments; added excipients
  • Azithromycin: updated available products, preparation, stability, comments; added excipients
  • Aztreonam: added excipients
  • Benzylpenicillin: revised administration
  • Caspofungin: updated available products, preparation, stability, comments, added excipients
  • Cefalotin: updated available products, preparation, stability, administration, comments; added excipients
  • Cefotaxime: updated preparation, stability, administration (added link to ANMF), compatibility, cautions, monitoring
  • Cefoxitin: revised available products, preparation, stability, administration, compatibility, cautions
  • Chloramphenicol: updated available products, preparation, stability, administration; added adverse effects, contraindication, cautions
  • Cidofovir: revised preparation, stability, administration; monitoring; added adverse effects
  • Ciprofloxacin: revised stability, administration, compatible fluids (added plasma-Lyte 148); added, adverse effects, monitoring, excipients
  • Darbepoetin alfa: revised storage, preparation, stability, monitoring, added excipients.
  • Denosumab: revised storage, preparation, stability, added monitoring and excipients.
  • Diazoxide: updated storage, compatibility, monitoring; added excipients
  • Dobutamine: updated available products, preparation, stability, comments; added excipients
  • Epoprostenol (Flolan): revised products, preparation (concentration, stability), administration (rates), compatibility, cautions, added excipients
  • Furosemide: revised available products, preparation, stability, comments, added excipients
  • Ganciclovir: updated stability, administration (added link to ANMF), comments
  • Glycopyrronium bromide: updated available products, pH, stability, compatibility, comments
  • Ketamine: revised available products, administration, added excipients
  • Lacosamide: revised administration, added excipients
  • Levetiracetam: revised products, rates for status epilepticus, comments, added excipients, neonates refer to ANMF
  • Levomepromazine: revised administration, cautions
  • Mesna: revised reparation, stability, administration; adverse effects, monitoring
  • Midazolam: revised products, preparation (added dilution example), stability, administration; compatibilities, adverse effects; added excipients, link to SCHN policy, ANMF, Product Information
  • Milrinone: revised available products, preparation, stability, compatibility, comments, added excipients.
  • Parecoxib: revised available products, preparation, stability, compatibility, added monitoring and excipients
  • Phenytoin: revised administration (minimum dilution maximum; rates) added link to ANMF, cautions
  • Piperacillin: updated available products, preparation, administration, stability, comments; added excipients
  • Rasburicase: revised preparation, administration (included fluid restriction)
  • Rifampicin: revised preparation, stability, administration, adverse effects, monitoring, added excipients.
  • Salbutamol: revised preparation, administration, compatible fluids (added plasma-Lyte 148); added excipients
  • Sildenafil: revised preparation, stability, administration; compatibilities, monitoring
  • Sodium chloride: revised products; comments
  • Suxamethonium: updated available products, storage, preparation, stability, comments; added link to ANMF, e-policy, Mercury brand PI (19A), excipients. 
  • Verapamil: revised storage, preparation, stability, administration; compatibilities  (added plasma-Lyte 148), monitoring
  • Vitamin C: updated available products, preparation, stability, administration, comments
  • Zoledronic acid: revised available products, preparation, stability, administration and cautions.

January-December 2019

New monographs

Full review and updated monographs
  • Anakinra
  • C1 Esterase Inhibitor
  • Famotidine
  • Fosaprepitant
  • Glycopyrronium bromide
  • Hydromorphone
  • Indometacin
  • Lacosamide
  • Methylene blue
  • Palivizumab
  • Rocuronium
  • Tocilizumab
  • Aciclovir: revised preparation, stability, administration and comments, added link to SCHN Aciclovir: Intravenous Drug Protocol and SCHN IV Extravasation Management Practice Guideline.
  • Alteplase: revised preparation, administration, compatibility, cautions
  • Amphotericin B-Liposomal: revised administration cautions
  • Argipressin (vasopressin): revised preparation, administration, cautions
  • Cefazolin: revised products, preparation, added intracameral use
  • Ceftriaxone: revised preparation
  • Daptomycin: revised administration
  • Defibrotide: revised administration
  • Esomeprazole: revised stability
  • Ferric carboxymaltose: revised administration and monitoring, added link to SCHN IV Extravasation Management Practice Guideline.
  • Flucloxacillin: revised stability, compatibility
  • Levetiracetam: revised preparation, stability, administration (included faster rate for status epilepticus) and comments; added link to SCHN Seizures-Acute management in infants and children practice guideline.
  • Levocarnitine: revised preparation, monitoring
  • Linezolid: revised storage and cautions
  • Micafungin: revised stability, administration, cautions
  • Naloxone: revised stability, administration, cautions
  • Omeprazole: revised  storage, preparation, cautions
  • Ondansetron: revised administration
  • Pancuronium: revised storage, stability, administration (included neonates), cautions
  • Pantoprazole: revised cautions
  • Phenobarbitone: revised  preparation, stability, administration
  • Phenytoin: minor edits
  • Potassium dihydrogen phosphate: revised preparation, administration, cautions
  • Propofol: revised products, preparation, stability, administration, cautions
  • Pyridoxine: revised products, preparation, stability, administration, cautions
  • Tacrolimus: added links to transplant protocols
  • Thiamine: revised products, administration, cautions
  • Tobramycin; revised administration, compatibility, cautions.
  • Tranexamic acid: revised continuous infusion and rates, cautions
  • Tranexamic acid: revised products, administration, cautions
  • Valproate: revised preparation and administration
  • Voriconazole: revised, preparation, stability, administration, cautions
  • Zinc chloride: revised  preparation, stability, administration, cautions

January– December 2018

New monographs

Full review and updated monographs
  • Aprotinin
  • Calcium folinate
  • Choriogonadotropin alfa
  • Daptomycin
  • Levosimendan
  • Mesna
  • Paliperidone
  • Posaconazole
  • Sildenafil
  • Vitamin B12
  • Amphotericin B Lipid complex: updated cautions
  • Amphotericin B liposomal: updated administration and cautions
  • Antithymocyte Globulin Equine: revised preparation, stability, administration, comments
  • Antithymocyte Globulin Rabbit: revised preparation, stability, administration, comments
  • Aztreonam: revised IV injection administration, neonates administration, monitoring, comments
  • Cefepime: updated brands, stability, administration
  • Ceftaroline: minor edits
  • Clindamycin: revised  preparation, administration, comments
  • Clonidine: revised preparation, administration, cautions
  • Colistin: updated stability, compatible fluids and comments
  • Cyclizine: updated administration and cautions
  • Diazepam: revised preparation, administration, caution
  • Flucloxacillin: revised stability, administration, included adverse effects
  • Furosemide: revised compatibility
  • Haloperidol: revised stability, administration, cautions
  • Hydrocortisone sodium succinate: updated compatibilities
  • Hydromorphone:
  • Lincomycin: revised stability, administration, comments
  • Lorazepam: revised cautions
  • Meropenem: updated brands, added neonatal guidelines
  • Metoclopramide: updated preparation and administration
  • Metronidazole: revised stability, administration, comments
  • Mycophenolate: revised storage, preparation, stability
  • Nimodipine: revised stability, administration, compatibility, cautions
  • Potassium chloride: revised available products, preparation, stability, administration
  • Phytomenadione: revised administration
  • Rantidine: revised  preparation, stability, administration, comments
  • Sodium nitroprusside: revised available products, storage, administration, comments
  • Teicoplanin: revised compatibility, cautions
  • Tobramycin: updated administration, at CHW recommend infusion over 30 minutes
  • Trimethoprim with sulfamethoxazole: revised maximum dilution
  • Tacrolimus: revised preparation, administration, cautions
  • Valproate sodium: revised products, preparation, stability, administration, comments

January– December 2017

New monographs

Full review and updated monographs
  • Amoxycillin with clavulanic acid
  • Ferric carboxymaltose (Ferinject)
  • Fomepizole
  • Ibuprofen
  • Iron polymaltose
  • Iron sucrose (Venofer)
  • Parecoxib
  • Prochlorperazine
  • Acetylcysteine
  • Alteplase
  • Amiodarone
  • Azithromycin
  • Calcium chloride
  • Ceftazidime
  • Clonazepam
  • Fentanyl
  • Fluconazole
  • Frusemide
  • Gentamicin
  • Hydrocortisone sodium succinate
  • Infliximab
  • Levocarnitine
  • Linezolid
  • Magnesium chloride
  • Magnesium sulfate
  • Methylprednisolone sodium succinate
  • Midazolam
  • Milrinone
  • Morphine
  • Noradrenaline
  • Oxycodone
  • Paracetamol
  • Phytomenadione
  • Promethazine
  • Sodium benzoate
  • Tacrolimus
  • Vancomycin
  • Voriconazole
  • Vitamin C
  • Zinc chloride
  • Zoledronic acid

January 2015– December 2016

New monographs

Full review and updated monographs
  • Adalimumab
  • Basiliximab
  • Caffeine citrate
  • Calcium gluconate
  • Ceftaroline fosamil
  • Cidofovir
  • Darbepoetin alfa
  • Diazoxide
  • Ertapenem
  • Haloperidol
  • Hyoscine hydrobromide
  • Lorazepam
  • Micafungin
  • Moxifloxacin
  • Pentamidine isethionate
  • Quinine dihydrochloride
  • Remifentanil
  • Somatotropin
  • Tramadol
  • Tranexamic acid
  • Verapamil
  • Vitamin C
  • Acetylcysteine
  • Acetazolamide
  • Aciclovir
  • Adenosine
  • Adrenaline
  • Alprostadil
  • Amikacin
  • Aminophylline
  • Amoxycillin
  • Ampicillin
  • Amphotericin B liposomal
  • Amphotericin B phospholipid complex
  • Azathioprine
  • Azithromycin
  • Benzylpenicillin
  • Benztropine
  • Calcium chloride
  • Caspofungin
  • Cefalotin
  • Cefepime
  • Cefotaxime
  • Cefoxitin
  • Ceftazidime
  • Ceftriaxone
  • Cephazolin
  • Chloramphenicol
  • Ciprofloxacin
  • Clindamycin
  • Clonidine
  • Cyclizine
  • Cyclosporin
  • Desmopressin
  • Dexamethasone
  • Diazepam
  • Diazoxide
  • Digoxin
  • Dobutamine
  • Dopamine
  • Epoprostenol
  • Erythromycin lactobionate
  • Esmolol
  • Flucloxacillin
  • Ganciclovir
  • Gentamicin
  • Immunoglobulin, normal
  • Hydrocortisone sodium succinate
  • Levocarnitine
  • Levomepromazine
  • Lorazepam
  • Magnesium chloride
  • Magnesium sulfate
  • Metaraminol
  • Metoclopramide
  • Naloxone
  • Noradrenaline
  • Octreotide
  • Omeprazole
  • Ondansetron
  • Pamidronate
  • Pantoprazole
  • Paracetamol
  • Pethidine
  • Phenobarbital
  • Phenytoin
  • Piperacillin with tazobactam
  • Potassium chloride
  • Pyridoxine
  • Ranitiine
  • Rasburicase
  • Ribavirin
  • Rifampicin
  • Salbutamol
  • Sodium bicarbonate
  • Sodium calcium  edetate
  • Sodium dihydrogen phosphate
  • Sodium nitroprusside
  • Sulfamethoxazole with trimethoprim
  • Suxamethonium
  • Teicoplanin
  • Thiopentone
  • Ticarcillin with clavulanic acid
  • Tobramycin
  • Urokinase
  • Vancomycin
  • Vasopressin
  • Vecuronium